Numerous tumor suppression molecules have been identified in two organisms highly resistant to oxidative damage. Several potential drug targets in translation suppression and RNA processing identified.

Three novel gene targets homogulous to E3 ubiquitinprotein ligase DTX3L have been identified. This enzyme protects cells exposed to DNA damaging agents, possibly by recruiting repair enzymes to the damage site.

Two natural killer (NK) cell enhancers have been identified. One protein product is a helices that enhances NK cell function and may be involved in growth inhibition. The other is an oxidative stress mediator and transcriptional repressor.

Lead ultraviolet (UV) tolerant species revealed 5 gene targets responsible for DNA photolyase production. DNA photolyases are repair enzymes that convert UV-damaged DNA to the original state and prevent tumor formation.